Modify your presets layout, name and blocks settings, load or save presets, and many more functions !
For AxeFx II/XL/XL+ control you will need a 3rd party MIDI interface.
For AX8, direct USB connection is needed as the AX8 does not support MIDI port sysex anymore !
AxeFx generation 1 are not supported.
A full description of the connection options is available here : http://wiki.fractalaudio.com/axefx2/index.php?title=FracPad